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Updated: Jun 15, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
Beyond pain: predictors of postoperative maladaptive behavior change in children
Michelle A Fortier1, Antonio M Del Rosario, Abraham Rosenbaum
1Department of Anesthesiology and Perioperative Care, University of California-Irvine, CA, USA. mfortier@choc.org
Insights
Postoperative behavior changes are common in children after surgery. Preexisting child factors, not just pain, predict these changes, aiding in prevention and management.
Area of Science:
- Pediatric Surgery
- Child Psychology
- Behavioral Science
Background:
- Maladaptive behavior changes in children post-surgery are documented.
- Previous studies often lack control for confounding variables like pain and surgical techniques.
Purpose of the Study:
- To determine the incidence of behavior change in children after surgery.
- To identify risk factors for postoperative behavior change, controlling for pain and surgical factors.
Main Methods:
- 260 children undergoing tonsillectomy and adenoidectomy were studied.
- Baseline data, pain, and behavioral recovery were assessed for two weeks post-surgery.
- Standardized anesthesia and surgical procedures were used with validated measures.
Main Results:
- 80.4% of children showed negative behavior changes on the first day home.
- Behavior changes persisted for two weeks in nearly one-third of children.
- Preexisting anxiety/depression, younger age, and inhibited temperament predicted specific behavioral issues.
Conclusions:
- Child-specific factors, beyond pain, predict postoperative behavior changes.
- Identifying these predictors can help prevent and manage behavioral recovery difficulties.
- This research offers insights into supporting children's adjustment after surgery.
Unlabelled:
OBJECTIVES & AIM: Using well-validated measures and controlling for potential confounding variables such as pain and surgical and anesthetic technique, the goal of this project was to identify the incidence of and risk factors for the development of behavior change in children after surgery.
Background:
Although researchers have described maladaptive behavior change following surgery, many previous studies are limited by potential confounding variables, including postoperative pain, type of surgery, and surgical and anesthetic procedure.
Methods:
Participants included 260 children undergoing tonsillectomy and adenoidectomy. Baseline and demographic data were collected prior to surgery and pain and behavioral recovery were recorded for 2 weeks following surgery. A standardized approach to anesthesia and surgical procedure was implemented and well-validated assessment measures were used.
Results:
On the first day at home following surgery, 80.4% of children exhibited negative behavior change. Nearly one-third of children continued to exhibit behavior changes 2 weeks after surgery. Logistic regression analyses that controlled for pain severity identified several predictors of behavior change: preexisting somatic and anxious/depressed problems predicted new onset postoperative general anxiety, chi(2) (8) = 20.10, P = 0.010; younger age predicted separation anxiety, chi(2) (4) = 20.41, P < 0.01; and inhibited temperament predicted postoperative sleep disturbance, chi(2) (2) = 9.19, P = 0.010.
Conclusions:
Individual child factors above and beyond pain predict maladaptive postoperative behavior change; identification of these predictors may be helpful in both preventing and ameliorating difficulties with behavioral recovery following surgery.
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