The effect of an educational leaflet on depressive patients' attitudes toward treatment

Improving patient adherence to antidepressant treatment is an important issue. Patients' attitudes toward symptoms, results, causes, disease course, and effective treatment of depression can influence their adherence to therapy. We aimed to assess the efficacy of an educational leaflet designed to improve patients' attitudes toward depression and antidepressant treatment. Participants were one hundred twenty-two outpatients of three psychiatric clinics in Japan who met the DSM-IV criteria for depression. Patients in the intervention group received an educational leaflet at the start of the study. Participants filled in The Antidepressant Compliance Questionnaire (ADCQ) and Beck Depression Inventory (BDI) before and after the intervention. Intervention group showed greater improvements on the total score of ADCQ, the score on the "positive beliefs regarding antidepressants" subscale. They maintained the scores on the "perceived doctor-patient relationship" subscale, where the control group lowered those scores. No significant difference in improvement in BDI scores was observed between groups. The intervention using an educational leaflet had a significant positive impact on patients' attitudes toward depression and antidepressant treatment. Our results indicate that the educational leaflet is an effective tool for enhancement of face-to-face education by medical professionals. Trial registration UMIN000002981, www.umin.ac.jp/ctr/index.htm.