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Updated: Jun 15, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Sequential changes in myocardial function after valve replacement for aortic stenosis by speckle tracking
Christian Rost1, S Korder, G Wasmeier
1University of Erlangen, Erlangen, Germany. rost.christian@gmx.net
Regional myocardial function significantly improves after aortic valve replacement (AVR) for aortic stenosis (AS). Speckle tracking echocardiography (STE) revealed distinct recovery patterns for longitudinal, radial, and circumferential functions over six months.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Mechanics
Background:
- Regional myocardial function can vary with different pathologies.
- Aortic stenosis (AS) significantly impacts cardiac function.
- Aortic valve replacement (AVR) is a critical intervention for severe AS.
Purpose of the Study:
- To evaluate longitudinal, radial, and circumferential myocardial function in AS patients before and after AVR using speckle tracking echocardiography (STE).
- To assess changes in diastolic function (E/e' ratio) post-AVR.
- To understand the temporal recovery patterns of myocardial function after AVR.
Main Methods:
- Prospective study involving 40 patients with severe AS undergoing AVR.
- Speckle tracking echocardiography (STE) used to measure longitudinal, radial, and circumferential strain (LS, RS, CS).
- Echocardiographic assessments performed pre-AVR, 1 week post-AVR, and 6 months post-AVR.
Main Results:
- Left ventricular mass decreased significantly 6 months post-AVR.
- Left ventricular ejection fraction remained unchanged.
- Strain values (LS, RS, CS) increased significantly by 6 months post-AVR (16%, 21%, 28% respectively).
- E/e' ratio significantly decreased 6 months post-AVR (26.1 to 15.9).
Conclusions:
- Myocardial function shows significant recovery after AVR in AS patients.
- Distinct recovery patterns exist for longitudinal, radial, and circumferential myocardial function.
- STE is a feasible and clinically important tool for assessing regional function post-AVR.
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