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Updated: Jun 15, 2026

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

Adipokines involvement in lung function.

B Gurzu¹, F E Zugun, M Costuleanu

¹School of Medicine, Department of Physiology, "Gr.T. Popa" University of Medicine and Pharmacy Iaşi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi

|March 6, 2010

Summary

This summary is machine-generated.

White adipose tissue secretes adipokines, hormones that may link obesity and lung disease. This study reviews adipokine roles in pulmonary function, focusing on key hormones like leptin and adiponectin.

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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

Area of Science:

Endocrinology
Pulmonology
Obesity Research

Background:

White adipose tissue is increasingly recognized as an endocrine organ.
Adipokines, hormones secreted by adipose tissue, are implicated in various physiological and pathological processes.
Obesity is a known risk factor for several lung diseases, suggesting a potential mediating role for adipokines.

Purpose of the Study:

To review the current data on the involvement of adipokines in pulmonary function.
To highlight the specific roles of key adipokines, including leptin, adiponectin, and others, in the context of lung health and disease.

Main Methods:

Literature review of studies investigating adipokines and lung function.
Analysis of data linking specific adipokines to respiratory parameters.
Focus on established and emerging adipokines such as leptin, adiponectin, TNF-alpha, VEGF, resistin, HGF, IL-6, angiotensinogen, and apelin.

Main Results:

Adipokines demonstrate significant influence on various aspects of pulmonary function.
Specific adipokines like leptin and adiponectin have well-documented roles, while others like apelin are emerging areas of research.
The collective data suggests a complex interplay between adipose tissue hormones and lung physiology.

Conclusions:

Adipokines represent a crucial link between obesity and lung pathophysiology.
Understanding adipokine-mediated mechanisms is vital for developing novel therapeutic strategies for obesity-related lung diseases.
Further research into the diverse roles of adipokines in pulmonary health is warranted.