[Experimental study regarding the involvement of vitamins in the development of the dentomaxilar system]

The severe deficiencies of maternal nutrition in vitamins, both before and during pregnancy, might induce severe alterations of developing teeth in embryos and very young rats. Thus, the morphologic analysis of embryonic preparations revealed blood vessels slightly widen out, without turgescence, increased cellular density with oedema of the conjunctive tissue, foamy aspect of cells from mesenchyma. The adult preparations presented decreased cellular density with important fibrosis and presence of foamy cells, lack of dentine formation with small and diffuse proteinic accumulations, rarefied blood vessels, lack of enamel formation.