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Updated: Jun 15, 2026

In Vitro Polymerization of F-actin on Early Endosomes
Published on: August 28, 2017
Contribution of rearranged actin structures to the spread of Ectromelia virus infection in vitro
A Boratynska1, L Martyniszyn, L Szulc
1Division of Immunology, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.
Abstract:
We describe here a contribution of virus-induced actin tails and filopodia in transmission of Ectromelia virus (ECTV) infection in permissive cells detected by the immunofluorescence and confocal microscopy. Immunoblot analysis revealed profoundly decreased beta-actin levels during ECTV replicative cycle in the infected cells 24 hrs post infection (p.i.). These results provided a basis for the further analysis of ECTV motion in the infected cells as well as for impact of ECTV infection on the cytoskeletal proteins.
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