Pharmacoeconomics of voriconazole
Carlos Rubio-Terrés1, Santiago Grau
1Health Value, Virgen de Aranzazu, 21, 28034 Madrid, Spain. crubioterres@healthvalue.org
Importance Of The Field:
The recent increase in the use of antineoplastic and immune suppressive agents and the use of broad-spectrum antibiotics, prosthetic interventions, organ transplants and more aggressive surgery have been related to a greater prevalence of invasive fungal infections (IFI). Over the past few years, several new antifungal therapies have become available for these patients. Pharmacoeconomic data can play a useful role in comparing the relative benefits of treatment.
Areas Covered In This Review:
This review summarizes all the available evidence regarding the pharmacoeconomics of voriconazole. A systematic review of pharmacoeconomic analyses through a non-restricted literature search was conducted (until May 2009).
What The Reader Will Gain:
The reader will gain a greater understanding of the pharmacoeconomics role of voriconazole.
Take Home Message:
The majority of economic analyses have shown that voriconazole is a more cost-effective alternative in the treatment of invasive fungal infections than the antifungal drugs with which it was compared.
Related Concept Videos
Pharmacokinetics: Overview
Dosage Regimens: Partial Pharmacokinetic Parameters
Pharmacokinetics: Drug–Food and Drug–Viral Interactions
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Therapeutic Drug Monitoring: Affecting Factors
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

