Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network.

Nature methods·2026

Same author

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif.

Structure (London, England : 1993)·2025

Same author

A multimodal platform for real-time neurochemical and electrophysiologic monitoring for intraoperative neurosurgical applications.

Biosensors & bioelectronics·2025

Same author

Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.

bioRxiv : the preprint server for biology·2025

Same author

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved TBM motif.

bioRxiv : the preprint server for biology·2025

Same author

Simultaneous enhancement of multiple functional properties using evolution-informed protein design.

Nature communications·2024

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Acrylic intraocular lens damage after folding using a forceps insertion technique.

Jay C Erie¹, Brant Newman, Michael A Mahr

¹Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA. erie.jay@mayo.edu

Journal of Cataract and Refractive Surgery

|March 6, 2010

Summary

Forceps folding of acrylic intraocular lenses (IOLs) can cause surface depressions. Coating the IOL with ophthalmic viscosurgical device (OVD) before insertion prevents these defects, preserving optic surface integrity.

More Related Videos

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Related Experiment Videos

Last Updated: Jun 15, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

Ophthalmology
Materials Science

Background:

Intraocular lens (IOL) insertion techniques are critical for visual outcomes.
Forceps manipulation during IOL insertion can potentially induce optic surface abnormalities.

Purpose of the Study:

To investigate surface abnormalities on acrylic intraocular lenses (IOLs) after folding with a forceps insertion technique.
To identify factors influencing the development of these IOL surface defects.

Main Methods:

Acrylic AcrySof MA60AC IOLs were microscopically examined before and after folding.
Differential interference contrast and reflected light imaging were employed.
The influence of temperature, time, and ophthalmic viscosurgical device (OVD) was assessed.

Main Results:

All IOLs exhibited smooth surfaces pre-folding.
Post-folding, all IOLs showed anterior optic surface depressions corresponding to forceps contact.
Depressions were exacerbated by IOL warming and forceps wear, and persisted for up to 72 hours.
OVD coating prior to forceps grasping prevented depression formation.

Conclusions:

The anterior optic surface of acrylic IOLs is susceptible to forceps-induced depressions.
Applying OVD to the IOL surface before grasping with metal forceps effectively prevents these abnormalities.