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Updated: Jun 15, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
Published on: January 7, 2019
Intracranial mucosa-associated lymphoid tissue (MALT) lymphoma
Sherise D Ferguson1, Wael Musleh, Sandeep Gurbuxani
1Section of Neurosurgery, MC 3026, The University of Chicago Hospital, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA.
Abstract:
Primary central nervous system lymphomas are a rare lymphoid tumor. A small proportion of these lymphomas are low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) subgroup. A primary MALT-lymphoma of the dura is very rare, with only a few reports. These low-grade tumors respond favorably to a combination of surgery and post-operative regional external beam radiotherapy. Differentiating these lesions from primary lymphomas or other dural-based lesions is therefore critical to determine clinical management and future prognosis. We report a 29-year-old patient with visual loss and dural-based MALT lymphoma and discuss the pertinent findings as well as the clinical management of patients with this unusual lesion.
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