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Published on: August 22, 2022
Glandular odontogenic cyst: systematic review.
1Division of Oral and Maxillofacial Radiology, Faculty of Dentistry, UBC, 2199 Wesbrook Mall, Vancouver V6T 1Z3, BC, Canada. dmacdon@interchange.ubc.ca
Dento Maxillo Facial Radiology
|March 6, 2010
Summary
This systematic review found glandular odontogenic cysts (GOCs) predominantly affect males and the mandible, with significant age variations across global populations. Recurrence is common, particularly outside sub-Saharan Africa.
Area of Science:
- Oral and Maxillofacial Pathology
- Odontogenic Cysts
- Systematic Review
Background:
- Glandular odontogenic cyst (GOC) is a rare but locally aggressive odontogenic tumor.
- Understanding its global variations in clinical and radiographic features is crucial for diagnosis and management.
Purpose of the Study:
- To systematically review the principal features of glandular odontogenic cysts (GOCs).
- To compare the frequencies of GOC features across four distinct global populations.
Main Methods:
- Systematic review of 18 reports encompassing 17 series of histopathologically confirmed GOC cases.
- Databases searched included PubMed (MEDLINE) and LILACS.
- Analysis focused on case series reported by authors within their caseload.
Main Results:
- GOCs occurred twice as frequently in males and affected the mandible nearly three times more often.
- Mean age at presentation was 44 years (Western group), but significantly younger in East Asian and sub-Saharan African groups.
- Significant differences in predilection for anterior jaw sextants (Western group), buccolingual expansion, and tooth displacement (sub-Saharan African group) were noted. Recurrence was 18% overall, but absent in the sub-Saharan African group.
Conclusions:
- Glandular odontogenic cysts exhibit a marked propensity for recurrence across most global regions.
- Clinical presentation includes swelling, predilection for anterior jaw sextants, and radiological findings of unilocular radiolucency with expansion.
- Tooth displacement, root resorption, and association with unerupted teeth are common features.
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