Eosinophilic esophagitis
Related Experiment Video
Updated: Jun 15, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
1The Children's Hospital, Denver, National Jewish Health, University of Colorado, Denver, School of Medicine, Aurora, CO 80045, USA. furuta.glenn@tchden.org
Abstract:
Eosinophilic esophagitis is a clinicopathological disease characterized by GERD-like symptoms, food impaction and dysphagia that occur with the histological finding of dense esophageal eosinophilia. Endoscopic features include linear furrows, white exudate and longitudinal shearing. Current concepts regarding the pathophysiology relate to a food allergen-induced overexpression of eosinophil-related cytokines including Il-5, IL-13 and eotaxin-3. Effective treatments include topical and systemic corticosteroids and dietary restrictions.
Related Concept Videos
Gastroesophageal Reflux Disease
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Achalasia
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

