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Updated: Jun 15, 2026

Measuring Constipation in a Drosophila Model of Parkinson's Disease
Published on: September 22, 2023
[Digestive disorders in Parkinson's disease: gastric atony, malabsorption and constipation]
L Pérez-Macho1, S Borja-Andrés
1Hospital Virgen de la Concha, Zamora, España.
Introduction:
Constipation and gastric atony are two of the most important non-motor symptoms of the disease. The first is made significant by its high prevalence and precocity, since it may appear several years before the motor symptoms, and the second because of the repercussions it has on the absorption of oral medication used in this disease.
Development:
Both the symptoms and their possible treatment are reviewed.
Conclusions:
In both cases treatment is based on hygienic-dietary measures that avoid substances that reduce peristalsis, prokinetic drugs like domperidone and, sometimes, infiltration of botulinum toxin, electrical stimulation or even surgical treatment.
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