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Published on: December 30, 2025
Mechanical and chemical thrombolysis of cerebral sinus thrombosis: evolution of a technique
Kim L Rickert1, Phillip D Purdy, Babu Guai Welch
1Department of Neurosurgery/Neuroradiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. kimrickert@aol.com
Cerebral sinus thrombosis, although uncommon, can be lethal if not recognized and treated quickly. Systemic heparin has become the treatment standard of care; however, some patients' conditions continue to deteriorate even while taking heparin. Endovascular techniques for thrombolysis have continued to evolve. The authors present a case of cerebral sinus thrombosis treated with a combination of mechanical and chemical intrasinus thrombolysis.
Cerebral sinus thrombosis, although uncommon, can be lethal if not recognized and treated quickly. Systemic heparin has become the treatment standard of care; however, some patients' conditions continue to deteriorate even while taking heparin. Endovascular techniques for thrombolysis have continued to evolve. The authors present a case of cerebral sinus thrombosis treated with a combination of mechanical and chemical intrasinus thrombolysis.
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