Related Experiment Video
Updated: Jun 15, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
Hodgkin's lymphoma presenting with heart failure: a case report
Zeinab Amirimoghaddam1, Malihe Khoddami, Nahid Dehghan Nayeri
1Faculty of Nursing and Midwifery, Tehran University of Medical Sciences, Nosrat St, Tohid Square, Tehran, 1419733171, Iran. nahid.nayeri@gmail.com.
Insights
Cardiac involvement in Hodgkin's lymphoma is rare and often overlooked. This case highlights a premortem diagnosis of heart metastasis presenting as heart failure in a child.
Area of Science:
- Oncology
- Cardiology
- Pediatric Hematology-Oncology
Background:
- Cardiac involvement in malignant lymphoma is an understudied area in oncology.
- Malignant lymphomas can metastasize to the heart, leading to various clinical presentations.
- Heart failure is a potential, though uncommon, manifestation of cardiac lymphoma.
Purpose of the Study:
- To report a rare case of cardiac involvement in pediatric Hodgkin's lymphoma.
- To emphasize the importance of considering cardiac metastasis in lymphoma patients presenting with heart failure.
- To highlight the challenges and significance of premortem detection of cardiac lymphoma.
Main Methods:
- Case report of an 8-year-old girl diagnosed with Hodgkin's lymphoma.
- Clinical presentation included systemic symptoms and signs of heart failure.
- Diagnostic workup revealed evidence of heart metastasis.
Main Results:
- The patient presented with a constellation of symptoms including abdominal distension, weakness, pallor, fever, edema, and hepatosplenomegaly.
- Signs of heart failure were a prominent feature of the clinical presentation.
- Diagnostic tests confirmed a rare instance of cardiac metastasis from Hodgkin's lymphoma.
Conclusions:
- Hodgkin's lymphoma can present with metastasis to the heart, even in pediatric cases.
- Premortem diagnosis of cardiac lymphoma is uncommon but crucial for appropriate management.
- This case underscores the need for increased awareness and investigation of cardiac involvement in lymphoma.
Introduction:
Cardiac involvement in malignant lymphoma is one of the least investigated subjects in oncology. This article reports a case of cardiac involvement in Hodgkin's lymphoma which presented as heart failure.
Case Presentation:
We report the case of an 8-year-old Afghan girl with Hodgkin's lymphoma. The disease presented with systemic signs and symptoms, including abdominal distension, weakness, pallor, chills, fever, generalized edema, hepatosplenomegaly and generalized lymphadenopathy, as well as signs of heart failure. Test results showed a rare form of heart metastasis.
Conclusion:
We report a case of Hodgkin's lymphoma with metastasis to the heart, detected premortem. Although the involvement of the heart in a malignancy is relatively common, premortem detection is unusual and only few studies have reported it in the literature.
Related Concept Videos
Heart Failure I: Introduction
Heart Failure III: Clinical Manifestations
Heart Failure IV: Classification and Diagnostic Evaluation
Heart Failure II: Pathophysiology
Pathophysiology of Heart Failure
Cardiomyopathy III: Hypertrophic Cardiomyopathy