Hodgkin's lymphoma presenting with heart failure: a case report

Zeinab Amirimoghaddam1, Malihe Khoddami, Nahid Dehghan Nayeri

  • 1Faculty of Nursing and Midwifery, Tehran University of Medical Sciences, Nosrat St, Tohid Square, Tehran, 1419733171, Iran. nahid.nayeri@gmail.com.

Insights

Cardiac involvement in Hodgkin's lymphoma is rare and often overlooked. This case highlights a premortem diagnosis of heart metastasis presenting as heart failure in a child.

Area of Science:

  • Oncology
  • Cardiology
  • Pediatric Hematology-Oncology

Background:

  • Cardiac involvement in malignant lymphoma is an understudied area in oncology.
  • Malignant lymphomas can metastasize to the heart, leading to various clinical presentations.
  • Heart failure is a potential, though uncommon, manifestation of cardiac lymphoma.

Purpose of the Study:

  • To report a rare case of cardiac involvement in pediatric Hodgkin's lymphoma.
  • To emphasize the importance of considering cardiac metastasis in lymphoma patients presenting with heart failure.
  • To highlight the challenges and significance of premortem detection of cardiac lymphoma.

Main Methods:

  • Case report of an 8-year-old girl diagnosed with Hodgkin's lymphoma.
  • Clinical presentation included systemic symptoms and signs of heart failure.
  • Diagnostic workup revealed evidence of heart metastasis.

Main Results:

  • The patient presented with a constellation of symptoms including abdominal distension, weakness, pallor, fever, edema, and hepatosplenomegaly.
  • Signs of heart failure were a prominent feature of the clinical presentation.
  • Diagnostic tests confirmed a rare instance of cardiac metastasis from Hodgkin's lymphoma.

Conclusions:

  • Hodgkin's lymphoma can present with metastasis to the heart, even in pediatric cases.
  • Premortem diagnosis of cardiac lymphoma is uncommon but crucial for appropriate management.
  • This case underscores the need for increased awareness and investigation of cardiac involvement in lymphoma.
Abstract

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