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Updated: Jun 15, 2026

Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

Published on: November 10, 2016

[New technologies applied to the medication-dispensing process, error analysis and contributing factors].

A M Alvarez Díaz¹, E Delgado Silveira, C Pérez Menéndez-Conde

¹Servicio de Farmacia, Hospital Universitario Ramón y Cajal, Madrid, Spain.

Farmacia Hospitalaria : Organo Oficial De Expresion Cientifica De La Sociedad Espanola De Farmacia Hospitalaria

|March 9, 2010

Summary

Implementing new technologies like Computerized Prescription Order Entry (CPOE) in medication dispensing systems significantly reduces errors. Automated Dispensing Systems (ADS) without CPOE showed the highest error rates, while CPOE integration improved safety across systems.

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Improving IV Insulin Administration in a Community Hospital

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Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

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Published on: November 10, 2016

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Area of Science:

Pharmacy practice research
Health informatics
Patient safety science

Context:

Medication dispensing errors pose a significant risk to patient safety.
Various dispensing systems exist, each with unique error profiles and contributing factors.
The integration of technology, such as Computerized Prescription Order Entry (CPOE), is transforming medication management.

Purpose:

To quantify and compare the prevalence of medication dispensing errors across different systems.
To identify the specific stages within the dispensing process where errors occur.
To determine the factors contributing to these dispensing errors.

Summary:

A prospective observational study analyzed 54,169 medication dispensing opportunities across five systems: Stock, Unitary-Dose Dispensing Systems (UDDS) with and without CPOE, and Automated Dispensing Systems (ADS) with and without CPOE.
Error rates varied significantly, with Stock (10.7%) and ADS without CPOE (20.7%) showing the highest rates, while CPOE-UDDS (2.2%) and CPOE-ADS (2.9%) demonstrated lower error prevalence.
Common errors included omission and incorrect drug amounts, with contributing factors ranging from stock-outs to communication deficiencies and personnel experience.

Impact:

The study highlights that technological advancements, particularly CPOE, enhance medication dispensing safety.
Findings provide crucial data for healthcare institutions to optimize dispensing workflows and technology adoption.
Reducing dispensing errors through system improvements directly contributes to improved patient outcomes and healthcare quality.