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Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.

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Related Experiment Video

Updated: Jun 15, 2026

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
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Published on: December 23, 2022

High-quality draft genome sequences of 28 Enterococcus sp. isolates.

Kelli L Palmer1, Karen Carniol, Janet M Manson

  • 1Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

Journal of Bacteriology
|March 9, 2010
PubMed
Summary

Twenty-eight draft genome sequences of enterococci, including common hospital-acquired infection and food fermentation species like Enterococcus faecalis and E. faecium, are now available. These sequences provide valuable resources for studying these important Gram-positive bacteria.

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Last Updated: Jun 15, 2026

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
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Published on: December 23, 2022

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A Duplex Digital PCR Assay for Simultaneous Quantification of the Enterococcus spp. and the Human Fecal-associated HF183 Marker in Waters

Published on: March 9, 2016

Area of Science:

  • Microbiology
  • Genomics
  • Bacterial Pathogenesis

Background:

  • Enterococci are Gram-positive bacteria known for causing hospital-acquired infections.
  • They also play roles as gut commensals and in food fermentations.
  • Understanding their genetic makeup is crucial for both clinical and industrial applications.

Purpose of the Study:

  • To make draft genome sequences of diverse enterococcal strains publicly available.
  • To facilitate research into the biology and pathogenicity of enterococci.
  • To support studies on the role of enterococci in infections and food science.

Main Methods:

  • Whole-genome sequencing was performed on 28 enterococcal strains.
  • Sequencing data was processed to generate draft genome assemblies.
  • Strains represented key species including Enterococcus faecalis, E. faecium, E. casseliflavus, and E. gallinarum.

Main Results:

  • Draft genome sequences for 28 enterococcal strains have been generated and are available.
  • The dataset includes strains from clinically relevant and industrially important species.
  • This provides a foundational resource for comparative genomics of enterococci.

Conclusions:

  • The availability of these draft genome sequences significantly enhances the study of enterococci.
  • Researchers can now explore genetic variations related to antibiotic resistance and virulence.
  • This resource will advance our understanding of enterococcal roles in health and industry.