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Awareness of hypercalcaemia in a hospital population?
A Frølich1, P McNair, I Transbøl
1Mineral Metabolic Research Group, Herlev County Hospital, Denmark.
Insights
Diagnosing hypercalcaemia is a significant challenge in hospitals. Despite its prevalence, clinicians frequently fail to identify elevated serum calcium levels, impacting patient care.
Area of Science:
- Clinical Medicine
- Endocrinology
- Laboratory Medicine
Background:
- Hypercalcaemia, defined as elevated serum calcium, is a common metabolic disturbance.
- Accurate identification of hypercalcaemia is crucial for timely diagnosis and management of underlying conditions.
Purpose of the Study:
- To assess the diagnostic accuracy and identification rates of hypercalcaemia in a hospital setting.
- To determine the proportion of hypercalcaemia cases correctly identified by clinicians.
Main Methods:
- Consecutive registration of all hypercalcaemia patients over a 6-month period.
- Analysis of serum calcium concentrations (albumin-corrected) against defined thresholds.
- Evaluation of clinician-requested serum calcium analyses and subsequent identification of hypercalcaemia.
Main Results:
- An estimated 2.6% of the hospital population had hypercalcaemia.
- Only 50% of patients with hypercalcaemia had a serum calcium analysis requested.
- The identification rate of hypercalcaemia varied widely (14%-96%) based on clinical diagnosis and severity, with an overall low detection rate (approximately 1 in 4 cases).
Conclusions:
- The study highlights a significant gap in the recognition and diagnosis of hypercalcaemia within a hospital environment.
- Clinician awareness and diagnostic practices require improvement to ensure adequate identification of hypercalcaemia.
- Further strategies are needed to enhance the detection of hypercalcaemia for better patient outcomes.
Abstract:
In a hospital population all patients with hypercalcaemia were registered consecutively during a 6-month period. Fifty per cent of the patients having hypercalcaemia, which was defined as serum calcium concentrations (albumin corrected) above normal mean + 3 standard deviations, had a serum calcium analysis requested. Of these between 14% and 96%, dependent on the clinical diagnosis and the degree of hypercalcaemia, had the hypercalcaemia identified. Since the prevalence of hypercalcaemia was estimated to be 2.6% and only about 1:4 was identified by the clinicians, correct diagnosis of hypercalcaemia seems to be a problem.
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