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Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
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Cigarette smoking as a risk factor for auditory problems.

Carolina Pamplona Paschoal1, Marisa Frasson de Azevedo

  • 1Hearing Disorder Program, Federal University of Sao Paulo.

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Cigarette smoking negatively impacts hearing, causing poorer auditory thresholds and reduced otoacoustic emissions. Smokers show increased risks of cochlear dysfunction and tinnitus, highlighting smoking

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Area of Science:

  • Ototolaryngology
  • Public Health
  • Audiology

Background:

  • Smoking is a significant public health issue.
  • The precise relationship between smoking and auditory problems remains unclear.

Purpose of the Study:

  • To investigate the effects of cigarette smoking on auditory thresholds.
  • To examine smoking's impact on otoacoustic emissions.
  • To assess the influence of the medial olivocochlear system's efferent inhibition.

Main Methods:

  • 144 adult participants (smokers and non-smokers) aged 20-31.
  • Evaluations included conventional and high-frequency audiometry.
  • Transient evoked otoacoustic emissions and suppression effects were measured.

Main Results:

  • Smokers exhibited worse auditory thresholds at 12.5 kHz (right ear) and 14 kHz (both ears).
  • Smokers showed reduced otoacoustic emission responses at 1 kHz (both ears) and 4 kHz (left ear).
  • Higher incidence of cochlear dysfunction and tinnitus was observed in smokers.

Conclusions:

  • Cigarette smoking demonstrates a detrimental effect on the auditory system.
  • Findings suggest smoking contributes to hearing impairment and cochlear issues.