[Bacterial vaginosis associated with Mobiluncus species in general practice]

Bacterial vaginosis is a common disease in outpatient gynaecological practice. Mobiluncus is one of the bacterial species recently described as associated with bacterial vaginosis. In our study, bacterial vaginosis and Mobiluncus sp. morphotype were identified by means of a Gram-stained smear of the vaginal secretions. 40 women with Mobiluncus sp. associated bacterial vaginosis were treated with 500 mg metronidazole three times daily for seven days. 38 (95%) of the 40 patients showed no signs or symptoms of bacterial vaginosis after treatment, and the Mobiluncus sp. morphotype was absent from the Gram-stained smears in all 38 women. At the second control visit one month later, the Gram-stain was normal and no complaints of discharge were noted. The treatment had a favourable effect on the following signs and symptoms of bacterial vaginosis: homogeneous discharge, spotting/postcoital/intermenstrual bleeding, low abdominal pain, pH greater than 4.7. The reduction of these symptoms was statistically significant. The treatment reduced the presence of Mobiluncus, G vaginalis and led to the restoration of Lactobacillus flora. Mobiluncus associated bacterial vaginosis can be treated successfully with 500 mg of metronidazole three times a day for seven days.