Related Experiment Video

Updated: Jun 15, 2026

Obtaining Highly Purified Toxoplasma gondii Oocysts by a Discontinuous Cesium Chloride Gradient
11:17

Obtaining Highly Purified Toxoplasma gondii Oocysts by a Discontinuous Cesium Chloride Gradient

Published on: November 3, 2009

[Retrospective clinical and laboratory study of the toxocariasis cases hospitalised between 2005 and 2008]

Roxana-Gabriela Bahnea1, A Ivan, E Cârdei

  • 1Disciplina de Parazitologie, Facultatea de Medicină si Farmacie Gr.T. Popa Iasi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|March 10, 2010
PubMed

Insights

This study on childhood toxocariasis in Iaşi found pulmonary symptoms were most common. Diagnosis involved hypereosinophilia and serology, with albendazole proving effective.

Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Parasitology
  • Epidemiology

Context:

  • Toxocariasis is a neglected tropical disease caused by the roundworm Toxocara.
  • Pediatric cases present with diverse clinical manifestations, impacting diagnosis and treatment.
  • Understanding the epidemiology and clinical spectrum in specific regions is crucial for public health.

Purpose:

  • To retroprospectively analyze clinical and laboratory findings in hospitalized pediatric toxocariasis cases.
  • To identify the most frequent clinical manifestations and laboratory abnormalities associated with toxocariasis in children.
  • To evaluate the efficacy of albendazole treatment in this cohort.

Summary:

  • A retroprospective study of 228 children hospitalized with toxocariasis between 2005 and 2008 in Iaşi.
  • Pulmonary symptoms (dyspnea, wheezing, cough) were most prevalent (80.70%), followed by digestive (abdominal pain, hepatosplenomegaly) and cutaneous manifestations.
  • Laboratory findings included high rates of hypereosinophilia (94.73%), hyperleukocytosis, and hypergammaglobulinemia. All cases were serologically confirmed.
  • Children responded well to albendazole treatment.

Impact:

  • Highlights the significant burden of toxocariasis in pediatric populations, particularly respiratory involvement.
  • Emphasizes the importance of considering toxocariasis in the differential diagnosis of children with unexplained respiratory and gastrointestinal symptoms.
  • Provides evidence for the effectiveness of albendazole in treating pediatric toxocariasis, informing clinical management guidelines.
Abstract

More Related Videos

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

Related Concept Videos

Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...