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Updated: Jun 15, 2026

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
[Compliance with bread fortified with vitamin D and calcium in elderly]
Roxana Costan1, E Zbranca, I Gotca
1Clinica de Endocrinologie, Facultatea de Medicină, Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi.
Aims:
The bakery products fortifying is an option for vitamin D daily intake supplementation. Our study has proposed the evaluation of the community-based elderly compliance to the daily administration of vitamin D fortified bread.
Material:
A group of 33 subjects between 58 to 89 years of age (71 +/- 6.9 years) who were living in a nursing home for elderly people, from Iaşi, Romania. DIET: The patients have received daily 100 g bund enriched with 125 mg (5000 UI) D3 vitamin and with calcium carbonate (320 mg of elemental calcium) during 12 months.
Method:
We had used 22 items questioner for evaluation of the Vitamin D supplementation compliance to the daily administration of the vitamin D fortified bread at the institutionalized patients.
Results:
Patients compliance was very good, 75% of these eating daily the fortified buns, 18% one at two days and the rest of the patients two days in a week. 76% of the patients have consumed the entire bun, 9% of the patients 3/4, 12% of the patient half bun and 3 % of the patients a quarter bun. For 79% of the patients the taste of the bread was good and 21% has complained some deficiencies. By the declaration of the 60% of the patients, the general health status was better at the end of the study.
Conclusion:
Alimentary supplementation through vitamin D and calcium bread fortification is a practical possibility for prevention of the population vitamin D deficit.
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