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Published on: June 11, 2012
[Severe hypoglycemia in children and adolescents suffering from type 1 diabetes mellitus]
Adriana Cosmescu1, Doina Felea, Silvia Mătăsaru
1Facultatea de Medicină, Disciplina Medicină de Familie, Universitatea de Medicina Si Farmacie "Gr.T. Popa" Iaşi .
Insights
Severe hypoglycemia affects over a quarter of children with type 1 diabetes, often due to delayed carbohydrate intake. Continuous education is key to preventing this dangerous complication.
Area of Science:
- Pediatrics
- Endocrinology
- Metabolic Disorders
Background:
- Severe hypoglycemia is a significant concern for children with type 1 diabetes and their families.
- Diabetic ketoacidosis and severe hypoglycemia are life-threatening medical emergencies.
Purpose of the Study:
- To determine the incidence of severe hypoglycemia in pediatric patients with type 1 diabetes.
- To identify the primary causes and risk factors associated with severe hypoglycemia episodes.
Main Methods:
- A cohort of 84 children and adolescents with type 1 diabetes was studied over 12 months.
- Data collected included hypoglycemia occurrence, risk factors, age, disease duration, insulin therapy, and metabolic control (HbA1c).
Main Results:
- 27.3% (23 out of 84) of patients experienced at least one severe hypoglycemia episode.
- The most common cause was delayed carbohydrate intake (47%), followed by high physical effort (19%) and excessive insulin (14%).
- Episodes occurred across a range of metabolic control levels (HbA1c 6.4%-9.1%).
Conclusions:
- Delayed carbohydrate intake is the leading preventable cause of severe hypoglycemia in this pediatric diabetic population.
- Continuous medical education for diabetic patients is crucial for preventing acute metabolic complications like severe hypoglycemia.
Unlabelled:
Hypoglycemia is the main fear of diabetic children and their parents. Severe hypoglycemia and diabetes ketoacidosis are medical emergencies that concern a patient's life prognosis.
Aim:
To determine the rate of occurrence of severe hypoglycemia and identification of the latter's causes.
Material And Method:
The study was carried out on a group of 84 children and adolescents suffering from type 1 diabetes, whom were investigated to determine the rate of occurrence of severe hypoglycemia episodes in the last 12 months, to identify their risk factors and to try to establish a relation between the onset of hypoglycemia and certain parameters like age, duration of disease, insulin therapy, metabolic control.
Results:
23 of the 84 patients reported at least one severe hypoglycemia in the last 12 months. 47% of the cases of hypoglycemia were caused by the patient's failure to observe the meal timetable, which led to delays in the carbohydrates intake, 19% were due to a high physical effort and 14% by excessive insulin administration. Most of the patients with severe hypoglycemia, that is 20 if 23, were on a multiple insulin injection treatment. As concerns the blood sugar balance, the mean Hb A1c values were between 6.4% and 9.1%, the severe hypoglycemia episodes occurred both in patients with very good metabolic control and in those with poor blood sugar balance.
Conclusions:
Severe hypoglycemia occurred in 27.3% of the children and adolescents suffering from type 1 diabetes, the most frequent cause revealed by this study being the delay in the carbohydrates intake. The prevention of this acute metabolic complication by a continuous medical education of diabetic patients is essential.
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