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[Evaluation of biological activity of a dermatological preparation with elaeagnus angustifolia flowers soft extract]
Laura Bucur1, Gh Tarălungă, Rodica Alexandrescu
1Disciplina Farmacognozie, Universitatea Ovidius Constantă, Facultatea de Medicină Dentară si Farmacie.
Unlabelled:
It was elaborated a dermatological preparation with 6% g Elaeagnus angustifolia flowers soft extract incorporated in water washable cream base.
Material And Method:
The soft extract contents resins with a wound healing activity, flavones and polyphenols with antioxidant activity. This extract was standardized in flavones (0.965-1.465%) and polyphenols (1.076-1.348%).
Results:
The dermatological preparation has a low antioxidant activity (AA% = 25.7%), half of soft extract antioxidant activity (AA% = 45.9%), tested by chemiluminescence method. The wound healing effect of the dermatological preparation was tested on rabbit scarred skin.
Conclusion:
The dermatological preparation had a superior activity than a control untreated or treated with washable cream base.
