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[Bioactive constituents from whole herbs of Vernonia cinerea (II)]
Huaxu Zhu1, Yuping Tang, Zhida Min
1School of Life Sciences, Nanjing Normal University, Nanjing 210024, China.
Objective:
To study the constituents of the whole herbs of Vernonia cinerea by bio-activity guided isolation with PC-12 model.
Method:
The constituents were separated by column chromatography and the structures were elucidated by spectroscopic methods.
Result:
Ten compounds were identified to be (-)-clovane-2,9-diol (1), caryolane-1,9beta-diol (2), apigenin (3), chrysoeriol (4), luteolin (5), thermopsoside (6), luteolin-7-O-beta-D-glucoside (7), quercetin(8), apigenin-4'-O-beta-D-glucoside (9), hyperin (10), beta-amyrin aceate (11), lupeol acetate (12).
Conclusion:
Compounds 1, 2, 6 and 10 were isolated from this genus for the first time.
