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Updated: Jun 15, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Continuous subcutaneous insulin infusion versus multiple daily injections in pregnant women with type 1 diabetes
Stella González-Romero1, Inmaculada González-Molero, Micaela Fernández-Abellán
1Endocrinology and Nutrition, Hospital Regional Universitario Carlos Haya, Avenida del Dr. Gálvez Ginachero S/N, Malaga, Spain. stellagr@telefonica.net
Background:
Continuous subcutaneous insulin infusion (CSII) may be an alternative to multiple daily injections (MDI) in pre-gestational diabetes during pregnancy. However, no clear improvement in obstetric and perinatal outcome has so far been established for CSII treatment.
Methods:
In a case-control study, 35 pregnancies treated with CSII and 64 pregnancies treated with MDI treatment were evaluated. Metabolic control and obstetric and perinatal outcome were compared.
Results:
Women in the CSII group improved their metabolic control (hemoglobin A1c before CSII, 7.83 +/- 0.97%; 3-6 months after, 6.77 +/- 0.61%; P < 0.05). Hemoglobin A1c before pregnancy was lower in the CSII group (6.62 +/- 0.60%) than in the MDI group (7.59 +/- 1.61%) (P < 0.05). No other significant differences, either in metabolic control of diabetes or in obstetric and perinatal outcome, were found.
Conclusions:
CSII treatment is safe in pregnancy, but it has not yet been associated with any improved pregnancy outcome.
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