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Related Concept Videos

Hyperglycemia01:29

Hyperglycemia

Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively manages...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Hypoglycemia01:26

Hypoglycemia

Hypoglycemia is a blood glucose level below 70 mg/dL. It commonly occurs in individuals using insulin or insulin-secreting drugs, but may also arise in non-diabetic conditions. People with type 1 diabetes are at the highest risk because they depend on exogenous insulin. People with type 2 diabetes are also at risk, especially when treated with insulin or medications such as sulfonylureas, which increase insulin release regardless of blood glucose levels. It develops when insulin levels exceed...

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Related Experiment Video

Updated: Jun 15, 2026

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Performance evaluation of the GlucoDr plus glucometer.

Dae-Hyun Ko1, Soo Lim, Sang Hoon Song

  • 1Department of Laboratory Medicine, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 300 Gumi-dong, Gyeonggi-do, Republic of Korea.

Diabetes Technology & Therapeutics
|March 10, 2010
PubMed
Summary

The new GlucoDr Plus glucometer demonstrates excellent precision and linearity for blood glucose self-monitoring. It is minimally affected by common interferents, making it a reliable tool for diabetes management.

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Last Updated: Jun 15, 2026

Improving IV Insulin Administration in a Community Hospital
12:08

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Published on: June 11, 2012

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing
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Area of Science:

  • Medical Devices
  • Biotechnology
  • Clinical Diagnostics

Background:

  • Strict glucose control is crucial for mitigating diabetes complications.
  • Self-monitoring of blood glucose (SMBG) is a cornerstone of diabetes treatment.
  • Numerous blood glucose meters are available, necessitating performance evaluations of new devices.

Purpose of the Study:

  • To evaluate the performance of the new GlucoDr Plus glucometer.
  • To assess the accuracy, precision, and reliability of the GlucoDr Plus for SMBG.

Main Methods:

  • Evaluation followed Clinical and Laboratory Standards Institute guidelines.
  • Interference testing included ascorbic acid, uric acid, maltose, and acetaminophen.
  • Performance was compared against six other glucometers, with hematocrit and PaO(2) effects assessed.

Main Results:

  • Imprecision (coefficients of variation) ranged from 0.99% to 4.98%.
  • Excellent linearity was observed across glucose concentrations from 32.5 to 786.5 mg/dL (R(2) = 0.9985).
  • Close concordance with the reference laboratory method (R(2) = 0.9869) and minimal interference effects were noted.

Conclusions:

  • The GlucoDr Plus exhibits acceptable precision and linearity.
  • The device is minimally affected by common interferents, hematocrit, and PaO(2).
  • GlucoDr Plus is a suitable option for diabetes self-monitoring of blood glucose.