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Related Concept Videos

Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Upper Respiratory Drugs: Decongestants01:27

Upper Respiratory Drugs: Decongestants

Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in various...
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Upper Respiratory Drugs: First and Second-Generation Antihistamines01:15

Upper Respiratory Drugs: First and Second-Generation Antihistamines

Antihistamines are a class of drugs widely used to alleviate the symptoms of allergies, such as sneezing, itching, and nasal congestion. They work by inhibiting the actions of histamine, which is released by immune cells in response to allergenic substances or tissue injuries.
Histamine binds to specific receptor sites, known as H1 receptors, on tissue cells, triggering inflammation and swelling. Antihistamines combat these effects by competing with histamine for these receptor sites. By...

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Related Experiment Video

Updated: Jun 15, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Drug-induced rhinitis.

M Varghese1, M C Glaum, R F Lockey

  • 1Department of Internal Medicine, Division of Allergy and Immunology, University of South Florida and the James A. Haley Veterans' Hospital, Tampa, FL 33612, USA. mvarghese78@gmail.com

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
|March 10, 2010
PubMed
Summary
This summary is machine-generated.

Drug-induced rhinitis, a non-allergic condition, has three main categories. Discontinuing the offending drug is recommended, with intranasal corticosteroids as a potential treatment.

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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Area of Science:

  • Otolaryngology
  • Pharmacology

Background:

  • Rhinitis involves nasal mucous membrane inflammation, categorized as allergic or non-allergic.
  • Drug-induced rhinitis is a specific type of non-allergic rhinitis.
  • Limited research exists solely on drug-induced rhinitis.

Purpose of the Study:

  • To review existing literature on drug-induced rhinitis.
  • To identify mechanisms and characteristics of drug-induced rhinitis.

Main Methods:

  • Conducted a literature search using PubMed and Medline.
  • Keywords included drug, medication, rhinitis, and related symptoms.
  • Cross-referenced findings with medical references like Epocrates.

Main Results:

  • Identified three categories of drug-induced rhinitis: local inflammatory, neurogenic, and idiopathic.
  • Rhinitis medicamentosa is a distinct subtype with unique features.

Conclusions:

  • Discontinuation or substitution of the causative medication is advised.
  • Intranasal corticosteroids are suggested for symptomatic treatment.
  • Intranasal antihistamines can be added if corticosteroids alone are insufficient.