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Optical coherence tomography of the larynx using the Niris system
Marc Rubinstein1, Esther L Fine, Ali Sepehr
1Department of Otolaryngology--Head and Neck Surgery and Beckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA.
This study demonstrates the feasibility of using a new optical coherence tomography (OCT) device for head and neck imaging. The OCT system effectively visualized laryngeal microstructures, aiding in the assessment of benign and premalignant conditions.
Area of Science:
- Otolaryngology
- Medical Imaging
- Optical Coherence Tomography
Background:
- Optical coherence tomography (OCT) is an emerging imaging modality.
- Previous OCT systems for head and neck applications were research-based.
Purpose of the Study:
- To evaluate the first commercial OCT device for head, neck, and upper aerodigestive tract imaging.
- To assess the feasibility and efficacy of this new OCT system compared to prior research systems.
Main Methods:
- The Niris OCT imaging system was used in 33 patients undergoing head and neck endoscopy.
- OCT images were acquired from various laryngeal structures using a flexible probe inserted via a laryngoscope.
Main Results:
- OCT successfully imaged laryngeal structures including vocal cords and epiglottis.
- Normal microstructures were identified in healthy tissue, and disruptions were visible in malignant pathologies.
Conclusions:
- The commercial OCT device is easily integrated into surgical settings with minimal setup.
- OCT imaging offers a reliable modality for surgical guidance, biopsy, and therapeutic decisions in laryngeal diseases.
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