Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 15, 2026

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
17:45

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Published on: February 26, 2012

Delayed matching-to-position performance in C57BL/6N mice.

Kazuhiro Goto1, Ryo Kurashima, Shigeru Watanabe

  • 1Japan Society for the Promotion of Science, Japan. kgoto@psy.flet.keio.ac.jp

Behavioural Processes
|March 10, 2010
PubMed
Summary

This study validates a delayed matching-to-position task for assessing spatial working memory in C57BL mice. The task effectively measures memory performance, showing expected results similar to other species.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conditioned place preference and conditioned place aversion in goldfish.

Behavioural pharmacology·2026
Same author

Correction: Quantifying nonmnemonic strategies in two-alternative forced-choice delayed matching and nonmatching-to-position tasks in mice (Mus musculus) using automated video tracking technologies.

Learning & behavior·2026
Same author

Quantifying nonmnemonic strategies in two-alternative forced-choice delayed matching and nonmatching-to-position tasks in mice (Mus musculus) using automated video tracking technologies.

Learning & behavior·2026
Same author

Correction: Information-seeking in mice (Mus musculus) during visual discrimination: study using a distractor elimination paradigm.

Animal cognition·2025
Same author

Bright and water-dispersible membrane probes enable visualization of cellular morphologies and dynamics in light-scattering tissues of living mice.

Chemical science·2025
Same author

Experimental analysis of choice behavior in Japanese eel (Anguilla japonica).

Behavioural processes·2025

Area of Science:

  • Neuroscience
  • Animal Behavior
  • Cognitive Psychology

Background:

  • Delayed matching-to-sample tasks are standard for spatial working memory assessment in various species.
  • Application of these tasks in mice has been limited, hindering comparative research.

Purpose of the Study:

  • To establish and validate a delayed matching-to-position task for assessing spatial working memory in C57BL mice.
  • To investigate the influence of task parameters on memory performance in mice.

Main Methods:

  • Mice (C57BL) were trained on a lever-pressing delayed matching-to-position task in an operant chamber.
  • Task parameters manipulated included sample response requirement, delay interval, and intertrial interval.
  • Accuracy was measured by the proportion of correct choices in the delayed matching phase.

More Related Videos

Assessment of Motor Balance and Coordination in Mice using the Balance Beam
07:03

Assessment of Motor Balance and Coordination in Mice using the Balance Beam

Published on: March 10, 2011

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

Related Experiment Videos

Last Updated: Jun 15, 2026

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice
17:45

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Published on: February 26, 2012

Assessment of Motor Balance and Coordination in Mice using the Balance Beam
07:03

Assessment of Motor Balance and Coordination in Mice using the Balance Beam

Published on: March 10, 2011

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

Main Results:

  • Spatial working memory performance showed a delay-dependent decrement.
  • Increased sample response requirements improved accuracy.
  • Intertrial interval duration did not affect accuracy, but preceding trials induced proactive interference.

Conclusions:

  • The delayed matching-to-position task is effective for assessing spatial working memory in laboratory mice.
  • Findings replicate established parametric effects observed in other species, validating the mouse model.
  • This validated task facilitates further research into the neurobiology of spatial working memory in mice.