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Updated: Jun 15, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

Congenital cytomegalovirus infection - An update

S Friedman1, E L Ford-Jones

  • 1Divisions of Neonatology and.

Paediatrics & Child Health
|March 10, 2010
PubMed

Insights

Cytomegalovirus (CMV) is a major cause of nonhereditary sensorineural hearing loss and intellectual disability in newborns. This review covers recent advancements in understanding CMV infection outcomes, risks, diagnosis, and treatment.

Area of Science:

  • Virology
  • Infectious Diseases
  • Pediatrics

Background:

  • Cytomegalovirus (CMV) is a leading infectious cause of congenital sensorineural hearing loss.
  • CMV infection is also a significant contributor to mental retardation.
  • Approximately 1% of all newborn infants are congenitally infected with CMV.

Purpose of the Study:

  • To review recent developments in the understanding of congenital Cytomegalovirus infection.
  • To summarize current knowledge on clinical outcomes, risk factors, diagnosis, and therapy for CMV infection.

Main Methods:

  • Literature review of recent studies on Cytomegalovirus.
  • Synthesis of information on clinical outcomes and risk factors.
  • Compilation of data on diagnostic methods and therapeutic approaches.

Main Results:

  • Congenital CMV infection remains a primary cause of nonhereditary sensorineural hearing loss.
  • CMV is a significant risk factor for developmental delays and intellectual disability.
  • Recent advancements have improved diagnostic accuracy and therapeutic strategies.

Conclusions:

  • Early diagnosis and intervention are crucial for managing congenital CMV infection.
  • Continued research is needed to further elucidate risk factors and optimize treatment.
  • Effective management strategies can mitigate the long-term consequences of CMV infection in newborns.

Keywords:
CytomegalovirusDried blood spotsGanciclovirPolymerase chain reaction

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