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Updated: Jun 15, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
Published on: September 25, 2017
Analysis of nitrosamines migration from condoms in the chinese market using a proper migration experiment
Di Feng1, Qingfeng Zhou, Xuelian Cheng
1Graduate School, Peking Union Medical College, Beijing, China.
Abstract:
In 2008, a total of 37 condoms was sampled from the Chinese market. Released nitrosamines and nitrosatable substances from the samples were monitored according to EN12868 method. Furthermore, to simulate the process of nitrosamines migration from condoms, a new and proper migration experiment was proposed in this study. N-nitrosodimethylamine, N-nitrosodiethylamine and N-nitrodibutylamine were found in almost all samples. The release levels of nitrosamines varied from 15.62 to 792.89 microg/kg. The proposed method is feasible, sensitive and accurate.
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