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Subdiaphragmatic extralobar pulmonary sequestration.

D J Lager1, K A Kuper, G K Haake

  • 1Department of Pathology, University of Iowa Hospitals and Clinics, Iowa 52242.

Archives of Pathology & Laboratory Medicine
|May 1, 1991
PubMed
Summary
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A rare case of extralobar pulmonary sequestration presented as a subdiaphragmatic mass in a neonate. This condition can be misdiagnosed as neuroblastoma, highlighting the need for careful pathological examination.

Area of Science:

  • Pediatric Pathology
  • Surgical Pathology
  • Neonatal Imaging

Background:

  • Retroperitoneal masses in neonates are uncommon and can present diagnostic challenges.
  • Neuroblastoma is a common retroperitoneal malignancy in infants, often considered in the differential diagnosis.
  • Pulmonary sequestration, a congenital lung malformation, typically occurs in the thorax.

Observation:

  • A left subdiaphragmatic retroperitoneal mass was detected antenatally via ultrasound in a 21-day-old infant.
  • Initial clinical suspicion and preoperative workup suggested neuroblastoma without metastatic disease.
  • Histopathological examination revealed the mass to be an extralobar pulmonary sequestration.

Findings:

  • Extralobar pulmonary sequestration can occur in the subdiaphragmatic retroperitoneal space.

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  • This presentation can mimic more common neonatal retroperitoneal lesions like neuroblastoma.
  • Accurate histological diagnosis is crucial for appropriate management.

    • Implications:

    • Pathologists should consider extralobar pulmonary sequestration in the differential diagnosis of neonatal subdiaphragmatic masses.
    • Awareness of this rare presentation can prevent misdiagnosis and guide appropriate clinical management.
    • This case underscores the importance of thorough histopathological evaluation in neonatal retroperitoneal masses.