Related Experiment Video

Updated: Jun 15, 2026

Investigation of Spatial Interaction Between Astrocytes and Neurons in Cleared Brains
05:17

Investigation of Spatial Interaction Between Astrocytes and Neurons in Cleared Brains

Published on: March 31, 2022

Flavonoids and astrocytes crosstalking: implications for brain development and pathology

Jader Nones1, Joice Stipursky, Sílvia Lima Costa

  • 1Laboratório de Neurobiologia Celular, Programa de Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Bloco F, Sala F15. Ilha do Fundão, Rio de Janeiro, RJ, Brazil.

Neurochemical Research
|March 10, 2010
PubMed
Summary

Flavonoids, abundant dietary antioxidants, may impact brain aging and neurodegenerative diseases by targeting astrocytes. Further research into these mechanisms could lead to new therapeutic strategies.

More Related Videos

Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions15:08

Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions

Published on: October 21, 2017

Isolation and Culture of Mouse Cortical Astrocytes11:25

Isolation and Culture of Mouse Cortical Astrocytes

Published on: January 19, 2013

Related Concept Videos

Neuron Structure01:30

Neuron Structure

Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...
The Blood-brain Barrier00:49

The Blood-brain Barrier

Overview
Glial Cells01:04

Glial Cells

Overview
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
Alzheimer Disease ll: Pathophysiology01:23

Alzheimer Disease ll: Pathophysiology

Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...