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Published on: September 8, 2021
[Adherence to therapy in multiple sclerosis and schizophrenia].
1Bayer Schering Pharma/Bayer Vital GmbH, Medizin, Neurologie/Immunologie/Ophthalmologie, 51368 Leverkusen. patrick.bussfeld@bayerhealthcare.com
Patient adherence to medical advice is crucial but often low in schizophrenia and multiple sclerosis (MS). Improving adherence requires further research and evidence-based interventions for these neurological and psychiatric conditions.
Area of Science:
- Neurology
- Psychiatry
- Health Services Research
Background:
- Adherence, defined as patient behavior aligning with healthcare recommendations, is critical for treatment efficacy.
- Factors influencing adherence are under-examined in neurological and psychiatric diseases.
- Inconsistent definitions and study periods lead to variable adherence rate data.
Purpose of the Study:
- To review and synthesize current understanding of adherence in schizophrenia and multiple sclerosis (MS).
- To identify existing and potential strategies for improving adherence in these patient populations.
- To highlight the need for further research and scientific evaluation of adherence interventions.
Main Methods:
- Review of existing literature on patient adherence in schizophrenia and MS.
- Analysis of reported adherence rates and influencing factors.
- Evaluation of current and proposed interventions for adherence improvement.
Main Results:
- Estimated adherence rates are approximately 50% for schizophrenia and 50-60% for MS.
- Interventions like psychoeducational programs and antipsychotic depot formulations show limited evidence in schizophrenia.
- MS nurse services are recognized for MS, but further research is needed to optimize adherence support.
Conclusions:
- Adherence rates in both schizophrenia and MS are notably low.
- There is a significant need for developing and scientifically evaluating new measures to enhance patient adherence in these conditions.
- Optimizing adherence interventions is essential for improving patient outcomes in neurological and psychiatric care.
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