Related Experiment Video
Updated: Jun 15, 2026

05:19
Modeling Cataract Surgery in Mice
Published on: December 1, 2023
Anesthesiologist intervention during cataract surgery under topical or peribulbar anesthesia: a propensity model
Marco Gemma1, Luigi Gioia, Elisa Dedola
1Anesthesia & Intensive Care Unit, San Raffaele Scientific Institute, Milano, Italy. gemma.marco@hsr.it
European Journal of Ophthalmology
|March 10, 2010
Summary
Peribulbar anesthesia (PA) and topical anesthesia (TLA) are feasible for monitored cataract surgery. While PA may lead to more agitation, it remains a valuable option for specific patient needs.
Area of Science:
- Ophthalmology
- Anesthesiology
- Surgical Care
Background:
- Monitored anesthesia care (MAC) is increasingly utilized for cataract surgery.
- Choosing between peribulbar anesthesia (PA) and topical anesthesia (TLA) involves balancing patient comfort and anesthesiologist intervention.
- Understanding the incidence and triggers for anesthesiologist intervention is crucial for optimizing patient safety and care during MAC for cataract surgery.
Purpose of the Study:
- To compare the frequency and reasons for anesthesiologist intervention during cataract surgery performed under peribulbar anesthesia (PA) versus topical anesthesia (TLA) within a monitored anesthesia care (MAC) setting.
- To evaluate the safety and feasibility of both PA and TLA in MAC for cataract surgery.
Main Methods:
- A prospective database of phacoemulsifications was analyzed, matching 97 patients who received PA with 97 who received TLA using a propensity model.
- Patient groups were matched for relevant comorbidities and pre-operative medications including antihypertensives, cardiologic, neurologic, psychiatric history, anxiolytics, and diabetes mellitus.
- The primary outcomes measured were the incidence of anesthesiologist intervention and the types of adverse events necessitating intervention.
Main Results:
- The overall incidence of anesthesiologist intervention did not differ significantly between the peribulbar anesthesia (38.14%) and topical anesthesia (27.84%) groups (p=0.123).
- A significant difference was observed in the incidence of patient agitation, which was higher in the topical anesthesia group (9.28%) compared to the peribulbar anesthesia group (24.74%) (p=0.004).
Conclusions:
- Monitored anesthesia care is a viable option for cataract surgery using either peribulbar anesthesia or topical anesthesia.
- Peribulbar anesthesia remains a suitable alternative for patients experiencing difficulties with eye fixation, involuntary blinking, or phacodonesis.
- Clinicians should anticipate a higher likelihood of agitation with peribulbar anesthesia and consider appropriate premedication with anxiolytics when this technique is chosen.
Related Concept Videos
Local Anesthetics: Common Agents and Their Applications
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
General Anesthesia: Overview
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Pharmacokinetics
The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...