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Updated: Jun 15, 2026

Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models

Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models

Published on: February 3, 2026

Imaging techniques in pancreatic tumors.

Mirko D'Onofrio¹, Anna Gallotti, Roberto Pozzi Mucelli

¹Department of Radiology, GB Rossi University Hospital, University of Verona, Verona, Italy. mirko.donofrio@univr.it

Expert Review of Medical Devices

|March 11, 2010

Summary

This review covers imaging techniques for diagnosing pancreatic tumors, highlighting contrast-enhanced ultrasound as a key first step. It also details advanced methods like CT and MRI for accurate staging and lesion characterization.

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Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models

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Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Published on: April 18, 2015

Area of Science:

Radiology
Oncology
Gastroenterology

Background:

Pancreatic tumors require accurate diagnostic imaging for effective management.
Conventional ultrasonography is the initial imaging modality for pancreatic lesions.

Purpose of the Study:

To review current imaging techniques for diagnosing pancreatic tumors.
To propose a diagnostic work-up algorithm for pancreatic lesions.

Main Methods:

Review of conventional ultrasonography, contrast-enhanced ultrasound, multidetector computed tomography (MDCT), MRI with MRCP, PET-CT, endoscopic ultrasound (EUS), and intraoperative ultrasonography.
Discussion of the role of image-guided fine-needle aspiration (FNA) or biopsy.

Main Results:

Contrast-enhanced ultrasound enhances the accuracy of initial pancreatic tumor assessment.
MDCT is the gold standard for solid pancreatic lesions and staging.
MRI with MRCP excels in evaluating cystic pancreatic lesions and the ductal system.
FNA/biopsy is often necessary for definitive diagnosis.
PET-CT, EUS, and intraoperative ultrasound are typically third-line investigations.

Conclusions:

A structured approach integrating various imaging modalities is crucial for pancreatic tumor diagnosis.
The proposed work-up algorithm aims to optimize the diagnostic pathway for pancreatic lesions.