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Related Concept Videos

Lytic Cycle of Bacteriophages01:30

Lytic Cycle of Bacteriophages

Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the lytic replication...
Microbe-Plant Interactions01:09

Microbe-Plant Interactions

Microbe-plant interactions represent a dynamic spectrum of associations shaped by intricate chemical signaling. These interactions can be neutral, beneficial, or detrimental, and profoundly influence plant physiology, growth, and ecosystem function. The plant microbiome, comprising bacteria, fungi, archaea, protists, and viruses, plays a pivotal role in mediating these effects through surface colonization, internal colonization, or systemic symbiosis.Mutualistic associations, particularly with...
Lysogenic Cycle of Bacteriophages00:43

Lysogenic Cycle of Bacteriophages

In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
Transgenic Plants02:50

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
DNA Bacteriophages01:26

DNA Bacteriophages

Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...

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Related Experiment Video

Updated: Jun 15, 2026

Bacteriophage Effectiveness for Biocontrol of Foodborne Pathogens Evaluated via High-Throughput Settings
07:22

Bacteriophage Effectiveness for Biocontrol of Foodborne Pathogens Evaluated via High-Throughput Settings

Published on: August 19, 2021

Phage therapy for plant disease control.

B Balogh1, Jeffrey B Jones, F B Iriarte

  • 1University of Florida, 1453 Fifield Hall, Plant Pathology Department, Gainesville, FL 32611, USA.

Current Pharmaceutical Biotechnology
|March 11, 2010
PubMed
Summary

Bacteriophages show promise for controlling plant bacterial diseases, overcoming challenges like resistance and persistence through innovative strategies. Integrated phage therapy offers a reliable solution for sustainable agriculture.

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Area of Science:

  • Agricultural Science
  • Microbiology
  • Plant Pathology

Background:

  • Bacterial plant diseases cause significant economic losses.
  • Controlling these diseases is difficult due to limited effective bactericides and emerging resistance.
  • Bacteriophages (phages) are emerging as a biological control agent for phytobacteria.

Purpose of the Study:

  • To evaluate the efficacy of bacteriophages in controlling economically important plant bacterial diseases.
  • To address the challenges associated with agricultural phage application, including bacterial resistance and phage persistence.
  • To explore strategies for enhancing phage therapy's reliability and effectiveness in agricultural settings.

Main Methods:

  • Application of phage mixtures and host-range mutant phages for resistance management.
  • Use of protective formulations and environmental modifications (e.g., avoiding sunlight) to increase phage persistence.
  • Integration of phage therapy into broader integrated disease management (IDM) strategies.

Main Results:

  • Phage therapy demonstrates potential for controlling phytopathogenic bacteria.
  • Resistance management approaches improve phage efficacy and reliability.
  • Strategies to enhance phage persistence contribute to better disease control outcomes.

Conclusions:

  • Bacteriophages represent a viable alternative to chemical bactericides for plant disease management.
  • Overcoming challenges in phage application is crucial for successful agricultural deployment.
  • Integrated phage therapy, combined with other control methods, offers a sustainable approach to plant disease control.