Y-chromosomal STR haplotypes in Central Thai population

Area of Science:

• Forensic genetics
• Population genetics
• Human genetics

Background:

• Y-STR loci are crucial for male lineage tracing.
• Establishing population-specific genetic databases is essential for forensic science.
• Previous Y-STR data for the central Thai population was limited.

Purpose of the Study:

• To characterize the genetic variation of 12 Y-STR loci in a central Thai male population.
• To generate a foundational dataset for forensic DNA profiling in Thailand.
• To assess the utility of these Y-STR loci for discriminating between individuals.

Main Methods:

• Genotyping of 12 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438, DYS439, DYS437) using the PowerPlex Y System.
• Analysis of allele frequencies and gene diversity for each locus.
• Calculation of haplotype diversity based on the combined 12 Y-STR loci.

Main Results:

• Allele frequencies and gene diversity were determined for all 12 Y-STR loci.
• The overall haplotype diversity for the combined 12 Y-STR loci was calculated to be 0.9996.
• The study successfully established a genetic profile for the central Thai male population.

Conclusions:

• The characterized Y-STR loci provide a robust genetic resource for the central Thai population.
• This data is directly applicable to routine forensic casework in Thailand.
• The high haplotype diversity indicates the potential for individual identification within this population.