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Related Concept Videos

Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...

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Related Experiment Video

Updated: Jun 15, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Gallbladder agenesis in a Chihuahua.

Hiroaki Kamishina1, Masaaki Katayama, Yasuhiko Okamura

  • 1Department of Veterinary Medicine, Iwate University, Iwate, Japan. kamicna@iwate-u.ac.jp

The Journal of Veterinary Medical Science
|March 11, 2010
PubMed
Summary

A Chihuahua diagnosed with gallbladder agenesis, a rare congenital condition, experienced liver enzyme elevations. This case highlights the importance of diagnostic imaging and surgical exploration for canine liver disease.

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Area of Science:

  • Veterinary Medicine
  • Canine Hepatology
  • Congenital Abnormalities

Background:

  • A 4-year-old male Chihuahua presented with anorexia and vomiting.
  • Persistent elevation of liver enzymes indicated underlying hepatic pathology.

Observation:

  • Ultrasonography suggested the absence of a gallbladder.
  • Exploratory laparotomy and retrograde cholangiography confirmed gallbladder agenesis.

Findings:

  • Hypoplasia of the right medial and lateral liver lobes was suspected.
  • Histopathology revealed bile ductule proliferation, portal fibrosis, and pseudolobular formation.

Implications:

  • This case underscores gallbladder agenesis as a differential diagnosis in dogs with liver enzyme abnormalities.
  • Understanding these congenital liver anomalies is crucial for accurate diagnosis and management in veterinary practice.