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Updated: Feb 10, 2026

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
Published on: May 12, 2023
Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?
Detlef Neumann1, Silke Beermann, Roland Seifert
1Institute of Pharmacology, Hannover Medical School, Hannover, Germany. neumann.detlef@mh-hannover.de
Abstract:
The histamine H4 receptor is expressed preferentially on immune cells, indicating a possible role of the H4 receptor in inflammation. Studies of inflammation in several animal models point to a pro-inflammatory function of the H4 receptor. However, studies on experimental murine bronchial asthma yielded conflicting results, a fact which is neglected in most H4 receptor publications. Therefore, the present review critically analyzes available data on the role of the H4 receptor in the murine bronchial asthma model.
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