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Updated: Jun 15, 2026

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
Published on: February 14, 2022
Substitution of corticosteroid with everolimus after lung transplantation: a pediatric case report
Thibaut Caruba1, Vanida Brunie, Véronique Bousseau
1Pharmacy Department, Hopital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris, France. thibaut.caruba@egp.aphp.fr
Abstract:
We report the case of a 12 year-old lung transplant recipient, in whom compressive epidural lipomatosis secondary to corticosteroid prompted us to replace prednisone with everolimus. Discontinuing corticosteroid treatment after lung transplantation is associated with a risk of graft rejection despite concomitant immunosuppressive therapy with tacrolimus and mycophenolate mofetil. During a follow-up of 18 months with everolimus instead of prednisone, we did not observe graft rejection. In parallel, all symptoms related to epidural compression disappeared within a month.
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