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Related Experiment Video

Updated: Jun 15, 2026

High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs

High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs

Published on: August 3, 2011

Profiling microRNA expression with the Illumina BeadChip platform.

Julissa Tsao¹, Patrick Yau, Neil Winegarden

¹UHN Microarray Center, Toronto, ON, Canada.

Methods in Molecular Biology (Clifton, N.J.)

|March 11, 2010

Summary

Researchers are uncovering the crucial roles of small noncoding RNAs, like microRNAs (miRNAs), in gene and protein expression regulation. Advanced microarray technology now enables high-throughput study of these vital molecules.

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Last Updated: Jun 15, 2026

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Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform

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Published on: November 30, 2016

Area of Science:

Molecular Biology
Genetics
Biochemistry

Background:

Gene and protein expression regulation involves complex mechanisms.
Microarray technology revolutionized global transcription studies in the 1990s.
The transcriptome encompasses more than just protein-coding genes.

Purpose of the Study:

To highlight the significance of small noncoding RNAs, specifically microRNAs (miRNAs), in gene and protein expression.
To emphasize the importance of measuring miRNA expression levels for understanding cellular responses.
To discuss the recent advancements in microarray technology for high-throughput miRNA analysis.

Main Methods:

Utilizing advanced microarray technology.
Performing high-throughput and parallel measurements.
Analyzing small noncoding RNA expression levels.

Main Results:

Small noncoding RNAs, including miRNAs, play a pivotal role in gene and protein expression control.
Each miRNA can target multiple genes, influencing cellular responses.
Recent technological advancements facilitate comprehensive miRNA expression profiling.

Conclusions:

Understanding miRNA expression is critical for a complete picture of cellular regulation.
High-throughput microarray technology enables efficient study of miRNAs.
Further research into miRNA functions will elucidate complex biological pathways.