Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antimicrobial Proteins01:23

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
iChip01:24

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electrical remodeling and cardiotoxicity precedes structural and functional remodeling of mouse hearts under hyperoxia treatment.

Journal of cellular physiology·2020
Same author

Carbon Dots Fabrication: Ocular Imaging and Therapeutic Potential.

Frontiers in bioengineering and biotechnology·2020
Same author

Cardiovascular Risks Associated with Gender and Aging.

Journal of cardiovascular development and disease·2019
Same author

Impact of hyperoxia on cardiac pathophysiology.

Journal of cellular physiology·2019
Same author

Polypharmacology or Promiscuity? Structural Interactions of Resveratrol With Its Bandwagon of Targets.

Frontiers in pharmacology·2018
Same author

Sex differences in murine cardiac pathophysiology with hyperoxia exposure.

Journal of cellular physiology·2018

Related Experiment Video

Updated: Jun 15, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
10:35

Production and Testing of Antimicrobial Peptides and Their Mimics

Published on: April 10, 2026

Recent patents on antimicrobial peptides.

Firoz K Pathan1, Deepa A Venkata, Siva K Panguluri

  • 1Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, Louisville, KY 40292, USA.

Recent Patents on DNA & Gene Sequences
|March 12, 2010
PubMed
Summary

Antimicrobial peptides offer a promising alternative to conventional antibiotics due to their broad-spectrum microbial killing ability. Recent patents highlight methods for identifying and utilizing these peptides, such as cathelicidin LL-37, for therapeutic applications like wound healing.

More Related Videos

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
10:13

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization

Published on: August 11, 2018

Related Experiment Videos

Last Updated: Jun 15, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
10:35

Production and Testing of Antimicrobial Peptides and Their Mimics

Published on: April 10, 2026

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
10:13

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization

Published on: August 11, 2018

Area of Science:

  • Biochemistry
  • Immunology
  • Microbiology

Background:

  • Antimicrobial peptides (AMPs) are crucial host defense molecules with broad-spectrum antimicrobial activity.
  • They play roles in inflammation, wound repair, and immune system regulation, in addition to their antibiotic functions.
  • AMPs can be large proteins or small peptides, acting via cell membrane disruption or targeting microbial macromolecules.

Purpose of the Study:

  • To review recent patents concerning antimicrobial peptides.
  • To highlight novel methods for identifying antimicrobial peptides and their therapeutic applications.

Main Methods:

  • Review of patent literature on antimicrobial peptides.
  • Identification of key patented antimicrobial peptides and their applications.

Main Results:

  • Patents cover methods for identifying antimicrobial activity, including specific peptides like papillosin and those from Halocynthia aurantium.
  • The use of cathelicidin LL-37 and its derivatives for wound healing is a significant focus.
  • Retrocyclins are also mentioned in the context of antimicrobial peptide research.

Conclusions:

  • Recent patents provide valuable insights into the identification and therapeutic potential of antimicrobial peptides.
  • These findings could accelerate the development of novel antimicrobial agents and treatments.
  • Exploiting patented antimicrobial peptides offers a promising avenue for combating microbial infections and promoting healing.