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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Clinical findings associated with abnormal lung function in children aged 3-26 months with recurrent respiratory
A S Pelkonen1, A Kotaniemi-Syrjänen, K Malmström
1Department of Allergology, Helsinki University Central Hospital, Helsinki, Finland. anna.pelkonen@hus.fi
Insights
Clinical findings like increased work of breathing and abnormal chest X-rays, not parent reports, predict lung function issues in young children with recurrent respiratory symptoms.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Clinical Diagnostics
Background:
- Recurrent lower respiratory tract symptoms are common in young children.
- Accurate assessment of lung function is crucial for diagnosis and management.
Purpose of the Study:
- To investigate associations between clinical findings, parent-reported symptoms, and lung function in children with recurrent lower respiratory tract symptoms.
Main Methods:
- 148 children (3-26 months) with recurrent respiratory symptoms underwent physical examination, chest radiography, whole-body plethysmography, and allergy testing.
- Lung function was assessed using functional residual capacity and specific conductance z-scores.
Main Results:
- 56% of children had abnormal lung function.
- Physical exam findings (increased work of breathing, noisy breathing) and abnormal chest X-rays were independently associated with abnormal lung function.
- Parent-reported symptoms, environmental exposures, and atopy were not linked to lung function abnormalities.
Conclusions:
- Clinical examination and chest radiography are important in evaluating early childhood respiratory disorders.
- Lung function testing may provide valuable objective data in preschool children with persistent respiratory symptoms.
Aim:
To evaluate whether there are any associations between parentally reported symptoms, clinical findings and lung function in young children with recurrent lower respiratory tract symptoms.
Methods:
In 2000-2003, 148 children, aged 3-26 months, with recurrent lower respiratory tract symptoms underwent physical examination, investigation of a chest radiograph, whole body plethysmography and skin prick testing to common food and inhalant allergens.
Results:
Lung function was considered abnormal (i.e. functional residual capacity z-score of > or =1.65 and/or specific conductance z-score of < or =-1.65) in 83 (56%) children. Findings of increased work of breathing (p < 0.001) and nonspecific noisy breathing sounds (p < 0.001) in the physical examination, as well as an abnormal chest radiograph (p = 0.028) were independently associated with abnormal lung function, explaining up to 34% of the variation in lung function. In contrast, parentally reported respiratory symptoms, environmental exposures or atopic trait were not associated with lung function abnormalities.
Conclusion:
The results of this study emphasize the importance of the meticulous clinical examination in the evaluation of early childhood respiratory disorders. As physical examination alone cannot predict lung function abnormalities reliably in preschool children with troublesome respiratory symptoms, lung function testing may be considered in such patients to obtain additional objective information.
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