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Related Experiment Video

Updated: Jun 15, 2026

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area
08:13

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area

Published on: February 19, 2018

Nickel oxide nanoparticles: a novel antioxidant.

Jyoti Prasad Saikia1, Samrat Paul, Bolin Kumar Konwar

  • 1Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, India. jyotizone@gmail.com

Colloids and Surfaces. B, Biointerfaces
|March 12, 2010
PubMed
Summary

Novel nickel oxide nanoparticles show antioxidant potential. Synthesized via self-propagating high-temperature synthesis, their antioxidant properties were confirmed using an in vitro DPPH assay for insoluble materials.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biochemistry

Background:

  • Oxidative stress is implicated in various biological conditions.
  • Developing novel antioxidant agents is crucial for therapeutic applications.
  • Inorganic nanoparticles offer unique properties for biomedical use.

Purpose of the Study:

  • To synthesize and characterize novel inorganic nickel oxide nanoparticles.
  • To evaluate the antioxidant capacity of these nanoparticles in a biological context.
  • To explore their potential application as antioxidants in biosystems.

Main Methods:

  • Nickel oxide nanoparticles were synthesized using the self-propagating high-temperature synthesis (SHS) method at 650°C.
  • Antioxidant properties were assessed using a modified 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay.

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  • The assay was adapted for evaluating insoluble solid materials.
  • Main Results:

    • The synthesis successfully produced nickel oxide nanoparticles.
    • The nanoparticles demonstrated significant antioxidant activity in the in vitro DPPH assay.
    • The modified DPPH method proved effective for assessing insoluble antioxidants.

    Conclusions:

    • Nickel oxide nanoparticles synthesized via SHS exhibit promising antioxidant properties.
    • These inorganic nanoparticles represent a potential new class of antioxidants for biosystems.
    • Further research is warranted to explore their therapeutic efficacy and safety.