Related Experiment Video
Updated: Jun 15, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Functionally uni-leaflet mitral valves in a family: a case series
Prathap Kanagala1, Stephanie Baker, Lawrence Green
1Department of Medical Physics, Grantham & District Hospital, Grantham, Lincolnshire, UK.
Abstract:
Functionally uni-leaflet mitral valves are extremely rare. In severe cases, they are considered incompatible with life beyond the neonatal period. We present a case series of three adults with almost complete absence of the posterior mitral valve leaflet and who are asymptomatic, with no more than mild mitral regurgitation. We believe that this is the first reported instance of such findings in a single family.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Mitral Stenosis I: Introduction
Mitral Valve Prolapse III: Nursing Management
Mitral Valve Prolapse II: Assessment and Management