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Related Experiment Video

Updated: Jun 15, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

The athlete and high altitude.

Richard Derby¹, Kevin deWeber

¹Tri-Service Military Primary Care Sports Medicine Program, Uniformed Services University, Bethesda, MD 20814, USA. rderby@usuhs.mil

Current Sports Medicine Reports

|March 12, 2010

Summary

This summary is machine-generated.

High-altitude illness (HAI) syndromes like AMS, HACE, and HAPE are critical for sports physicians to understand. Prompt recognition and proven therapies, alongside acclimatization, are key to managing these altitude-related conditions.

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Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

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Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method

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Published on: February 2, 2024

Area of Science:

Sports Medicine
Altitude Physiology

Background:

Athlete participation in high-altitude environments is increasing.
Understanding high-altitude illness (HAI) syndromes is crucial for sports physicians.

Purpose of the Study:

To outline the key HAI syndromes: acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and high-altitude pulmonary edema (HAPE).
To emphasize the importance of recognizing and treating HAI effectively.
To discuss preventive strategies and altitude/hypoxic training.

Main Methods:

Review of high-altitude illness syndromes occurring above 2500 m.
Discussion of incidence, severity factors (altitude, ascent rate), and clinical recognition.
Overview of therapeutic and prophylactic interventions.

Main Results:

HAI incidence and severity increase with altitude and ascent rate.
Acclimatization is the primary prevention strategy.
Specific medications (acetazolamide, dexamethasone, nifedipine, etc.) aid prevention.

Conclusions:

Sports physicians must be knowledgeable about HAI syndromes and their management.
Prompt treatment and acclimatization are vital for athlete safety at altitude.
Familiarity with altitude/hypoxic training practices is also essential for sports physicians.