The cosmetic ingredient review self-regulatory safety program.
W F Bergfeld1, R L Elder, A L Schroeter
1Department of Dermatology, Cleveland Clinic Foundation, Ohio.
Dermatologic Clinics
|January 1, 1991
Summary
The Cosmetic Ingredient Review (CIR) program has scientifically assessed cosmetic ingredient safety for 13 years, prioritizing frequently used and biologically active chemicals. This review process demonstrates a robust system for addressing potential safety concerns with cosmetic ingredients.
Area of Science:
- Cosmetic Science
- Toxicology
- Regulatory Science
Background:
- The cosmetic industry utilizes a vast array of chemical ingredients.
- Ensuring the safety of these ingredients is paramount for public health.
- A systematic approach to safety assessment is necessary.
Purpose of the Study:
- To evaluate the effectiveness and history of the Cosmetic Ingredient Review (CIR) program.
- To assess the CIR's methodology for prioritizing cosmetic ingredient safety reviews.
- To determine the CIR's capability in addressing cosmetic ingredient safety concerns.
Main Methods:
- The CIR employs a prioritization method based on ingredient usage frequency and biological activity.
- A comprehensive review of 310 cosmetic ingredients has been completed.
- 33 additional ingredients are currently under review.
Main Results:
- The CIR has successfully reviewed cosmetic ingredient safety over a 13-year period.
- The prioritization method effectively identifies key chemicals for review.
- A significant number of cosmetic ingredients have undergone scientific safety assessment.
Conclusions:
- The CIR has established a scientifically sound process for cosmetic ingredient safety evaluation.
- The CIR functions as a vital system for documenting, reviewing, and analyzing ingredient safety.
- The CIR's methodology provides a framework for addressing existing and potential safety issues in cosmetic ingredients.
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