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Published on: June 28, 2021
Wernicke's encephalopathy during total parenteral nutrition in a child with acute lymphoblastic leukemia and acute
S Muwakkit1, C Al-Aridi, R Saab
1Department of Pediatrics, Medical Center, American University of Beirut, Beirut, Lebanon. sm03@aub.edu.lb
Abstract:
We herein describe a 16-year-old child with acute lymphoblastic leukemia and acute pancreatitis who developed Wernicke's encephalopathy secondary to prolonged total parenteral nutrition (TPN) that lacked vitamin B1 supplementation. The patient showed a direct and complete response to thiamine therapy. Diagnostic challenges are discussed and recommendations for prophylactic vitamin B1 supplementation in children with leukemia who are placed on TPN are made.
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