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[Chondrocalcinosis].

Pascal Richette1, Thomas Bardin

  • 1Université Paris-7, UFR médicale, AP-HP, hôpital Lariboisière, Fédération de rhumatologie, 75475 Paris Cedex 10. pascal.richette@lrb.aphp.fr

La Revue Du Praticien
|March 13, 2010
PubMed
Summary
This summary is machine-generated.

Chondrocalcinosis is crystal deposition in cartilage, often presenting as pseudogout or chronic arthritis. Aging is a key risk factor, but metabolic disorders can also cause this condition.

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Area of Science:

  • Rheumatology
  • Radiology
  • Crystal Arthropathies

Context:

  • Chondrocalcinosis involves calcium pyrophosphate crystal deposition in cartilage.
  • It is visualized on plain radiographs.
  • Clinical manifestations range from acute synovitis (pseudogout) to chronic arthritis, potentially causing severe disability.

Purpose:

  • To define chondrocalcinosis and its clinical presentations.
  • To identify risk factors for chondrocalcinosis.
  • To highlight associations with metabolic disorders.

Summary:

  • Chondrocalcinosis is characterized by calcium pyrophosphate crystal deposition in cartilage.
  • The sporadic form is most common, with aging as the primary risk factor, affecting 7-10% of individuals around 60.
  • Secondary causes include hereditary hemochromatosis, hyperparathyroidism, and hypomagnesemia, particularly in younger patients.

Impact:

  • Understanding chondrocalcinosis aids in diagnosing and managing crystal-induced arthropathies.
  • Identifying risk factors like aging and metabolic disorders improves patient stratification.
  • Recognizing secondary causes is crucial for timely and appropriate treatment interventions.